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Anti-IBDV Capsid protein VP2 Polyclonal Antibody (VK127014)

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Overview
Catalog No.VK127014
Description
Anti-IBDV Capsid protein VP2 Polyclonal Antibody (VK127014) is a rabbit polyclonal antibody detecting IBDV Capsid protein VP2. Suitable for Avian infectious bursal disease virus.
Species reactivityInfectious bursal disease virus (IBDV)
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant IBDV Capsid protein VP2 (Thr2-Ile448).
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession QKI85211.1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Capsid protein VP2 is a ~64 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s).

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Anti-IBDV Capsid protein VP2 Polyclonal Antibody

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