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Anti-IGHMBP2 Polyclonal Antibody (HA628014)

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Overview
Catalog No.HA628014
Description
Anti-IGHMBP2 Polyclonal Antibody (HA628014) is a rabbit polyclonal antibody detecting DNA-binding protein SMUBP-2; 3.6.4.12; 3.6.4.13; ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2; IGHMBP2; SMBP2; SMUBP2 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human IGHMBP2 (Met1-Val440).
Target DNA-binding protein SMUBP-2; 3.6.4.12; 3.6.4.13; ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2; IGHMBP2; SMBP2; SMUBP2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P38935, Q9EQN5, P40694
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

DNA-binding protein SMUBP-2 (IGHMBP2) is a ~109 kDa protein. 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.

1. Guenther, UP. et al. (2009) Human molecular genetics 18, 1288-300. PMID: 19158098
2. Jaudzems, K. et al. (2012) Journal of molecular biology 424, 42-53. PMID: 22999958
3. Kanaan, J. et al. (2018) Nature communications 9, 3752. PMID: 30218034
4. Fukita, Y. et al. (1993) The Journal of biological chemistry 268, 17463-70. PMID: 8349627
5. de Planell-Saguer, M. et al. (2009) Human molecular genetics 18, 2115-26. PMID: 19299493
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-IGHMBP2 Polyclonal Antibody

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