Anti-Human IL-21 Polyclonal Antibody (HV658014)

Name: Anti-Human IL-21 Polyclonal Antibody
Brand: abinScience
SKU: HV658014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV658014

Description

Anti-IL21 Polyclonal Antibody (HV658014) is a rabbit polyclonal antibody detecting IL21 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IL21 (Leu23-Ser162).

Target

IL-21, Interleukin-21, IL21, Za11

Purification

Purified by antigen affinity column.

Accession

Q9HBE4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504

2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704

Note

For research use only.

Images

References

Datasheet