Anti-IMPDH2 Polyclonal Antibody (HY229014)

Name: Anti-IMPDH2 Polyclonal Antibody
Brand: abinScience
SKU: HY229014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HY229014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human IMPDH2 (Asp226-Phe514).

Target

IMPDH-II, IMPD 2, IMPD2, IMPDH2, IMPDH 2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2

Purification

Purified by antigen affinity column.

Accession

P12268

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) is a ~55 kDa protein. Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

1. Hager, PW. et al. (1995) Biochemical pharmacology 49, 1323-9. PMID: 7763314

2. Carr, SF. et al. (1993) The Journal of biological chemistry 268, 27286-90. PMID: 7903306

3. McLean, JE. et al. (2004) The Biochemical journal 379, 243-51. PMID: 14766016

Note

For research use only.

Images

References

Datasheet

Anti-IMPDH2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-IMPDH2 Polyclonal Antibody (HY229014)

Overview

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References

Datasheet

SDS

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