

| Catalog No. | VK560023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270) [SAA2270] (VK560023) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA. Suitable for Influenza A virus.
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| Species reactivity | Influenza A virus | ||||
| Applications | ELISA | ||||
| Host species | Alpaca | ||||
| Isotype | VHH-His | ||||
| Clone ID | SAA2270 | ||||
| Clonality | Monoclonal | ||||
| Target | Polymerase acidic protein, RNA-directed RNA polymerase subunit P2, PA | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >90% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P03427 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Polymerase basic protein 2 (RNA polymerase complex) is a ~85 kDa protein. Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270)
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