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Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA2270) (VK560023)

Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA2270)
Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA2270)
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Overview
Catalog No.VK560023
Description
Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270) [SAA2270] (VK560023) is a alpaca monoclonal antibody detecting RNA-directed RNA polymerase subunit P2 in ELISA. Suitable for Influenza A virus.
Species reactivityInfluenza A virus
ApplicationsELISA
Host speciesAlpaca
IsotypeVHH-His
Clone IDSAA2270
Clonality Monoclonal
Target Polymerase acidic protein, RNA-directed RNA polymerase subunit P2, PA
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P03427
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Polymerase basic protein 2 (RNA polymerase complex) is a ~85 kDa protein. Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.

Note For research use only.
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  • Anti-Influenza A virus RNA polymerase complex Recombinant Nanobody (SAA2270)

    SDS-PAGE

    SDS-PAGE for Anti-Influenza A virus RNA polymerase complex Nanobody (SAA2270)

References
Formula
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