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Anti-ITLN1 Polyclonal Antibody (HV600014)

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Overview
Catalog No.HV600014
Description
Anti-ITLN1 Polyclonal Antibody (HV600014) is a rabbit polyclonal antibody detecting ITLN1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ITLN1 (Cys31-Gly253).
Target INTL, ITLN-1, Intestinal lactoferrin receptor, ITLN, LFR, Intelectin-1, ITLN1, Omentin, Galactofuranose-binding lectin, Endothelial lectin HL-1
Purification Purified by antigen affinity column.
Accession Q8WWA0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Intelectin-1 (ITLN1) is a ~34 kDa protein. Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind human glycans. Probably plays a role in the defense system against microorganisms (Probable).

1. Tsuji, S. et al. (2001) The Journal of biological chemistry 276, 23456-63. PMID: 11313366
2. Wesener, DA. et al. (2015) Nature structural & molecular biology 22, 603-10. PMID: 26148048
3. Yang, RZ. et al. (2006) American journal of physiology. Endocrinology and metabolism 290, E1253-61. PMID: 16531507
4. Suzuki, YA. et al. (2001) Biochemistry 40, 15771-9. PMID: 11747454
5. Akiyama, Y. et al. (2013) Journal of biochemistry 154, 437-48. PMID: 23921499
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-ITLN1 Polyclonal Antibody

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