Anti-JUNV Glycoprotein GP1 Recombinant Antibody (CR1-28) (VK721053)

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100ug
1mg

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Datasheet
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Overview

Catalog No.

VK721053

Description

Anti-JUNV Glycoprotein GP1 Antibody (CR1-28) [CR1-28] (VK721053) is a human monoclonal antibody detecting GP1 in ELISA, Neutralization.

Species reactivity

Junin mammarenavirus (JUNV)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1

Clone ID

CR1-28

Clonality

Monoclonal

Target

GP1, Glycoprotein G1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P26313

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Pre-glycoprotein polyprotein GP complex (GP1) is a ~55 kDa protein. Functions as a cleaved signal peptide that is retained as the third component of the GP complex (GP-C). Helps to stabilize the spike complex in its native conformation. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of G1 and G2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

1. York, J. et al. (2004) Journal of virology 78, 10783-92. PMID: 15367645

2. York, J. et al. (2006) Journal of virology 80, 7775-80. PMID: 16840359

Note

For research use only

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