Anti-LSS Polyclonal Antibody (HW356014)

Name: Anti-LSS Polyclonal Antibody
Brand: abinScience
SKU: HW356014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW356014

Description

Anti-LSS Polyclonal Antibody (HW356014) is a rabbit polyclonal antibody detecting LSS in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LSS (Asp388-Pro549).

Target

OSC, Lanosterol synthase, hOSC, Oxidosqualene--lanosterol cyclase, 2, 3-epoxysqualene--lanosterol cyclase, LSS

Purification

Purified by antigen affinity column.

Accession

P48449

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Lanosterol synthase (LSS) is a ~83 kDa protein. Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.

1. Ruf, A. et al. (2004) Biochemical and biophysical research communications 315, 247-54. PMID: 14766201

2. Zhao, L. et al. (2015) Nature 523, 607-11. PMID: 26200341

3. Baker, CH. et al. (1995) Biochemical and biophysical research communications 213, 154-60. PMID: 7639730

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-LSS polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate

References

Datasheet

Anti-LSS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-LSS Polyclonal Antibody (HW356014)

Overview

Images

References

Datasheet

SDS

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