

| Catalog No. | HV554014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-LY96 Polyclonal Antibody (HV554014) is a rabbit polyclonal antibody detecting LY96 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human LY96 (Glu17-Asn160). | ||||||||
| Target | Ly-96, ESOP-1, MD2, Lymphocyte antigen 96, Protein MD-2, LY96, ESOP1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9Y6Y9 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Lymphocyte antigen 96 (LY96) is a ~18 kDa protein. Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. 1. Ohto, U. et al. (2007) Science (New York, N.Y.) 316, 1632-4. PMID: 17569869 2. Kim, HM. et al. (2007) Cell 130, 906-17. PMID: 17803912 3. Dziarski, R. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 1938-44. PMID: 11160242 4. Visintin, A. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 12156-61. PMID: 11593030 5. Shimazu, R. et al. (1999) The Journal of experimental medicine 189, 1777-82. PMID: 10359581 | ||||||||
| Note | For research use only. |
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