

| Catalog No. | HT080014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MAFG Polyclonal Antibody (HT080014) is a rabbit polyclonal antibody detecting MAFG in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Chicken.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MAFG (Met1-Ser162). | ||||||||
| Target | V-maf musculoaponeurotic fibrosarcoma oncogene homolog G, Transcription factor MafG, MAFG, hMAF | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O15525 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Transcription factor MafG is a ~17 kDa protein. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NFE2L2. Activates globin gene expression when associated with NFE2L2. 1. Hung, HL. et al. (2001) The Journal of biological chemistry 276, 10715-21. PMID: 11154691 2. Johnsen, O. et al. (1996) Nucleic acids research 24, 4289-97. PMID: 8932385 3. Johnsen, O. et al. (1998) Nucleic acids research 26, 512-20. PMID: 9421508 | ||||||||
| Note | For research use only. |
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