

| Catalog No. | HS779014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MAPK6 Polyclonal Antibody (HS779014) is a rabbit polyclonal antibody detecting MAPK6 in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, Pongo abelii, and Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MAPK6 (Met1-Met316). | ||||||||
| Target | p97-MAPK, ERK3, PRKM6, Mitogen-activated protein kinase 6, MAP kinase isoform p97, MAPK 6, ERK-3, MAP kinase 6, Extracellular signal-regulated kinase 3, MAPK6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q16659 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Mitogen-activated protein kinase 6 (MAPK6) is a ~82 kDa protein. Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle. | ||||||||
| Note | For research use only. |
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