

| Catalog No. | VK735014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Lake Victoria marburgvirus (MARV) (Marburg virus) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant MARV VP40/Marburg VP40 (Met1-Val303). | ||||||||
| Target | Matrix protein VP40, Marburg VP40, mVP40, Membrane-associated protein VP40, VP40 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P35260 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Matrix protein VP40 (Marburg VP40) is a ~33 kDa protein. Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 facilitates virus budding. The interaction with the nucleocapsid and the plasma membrane may also facilitate virus budding. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. 1. Shepley-McTaggart, A. et al. (2021) Viruses 13. PMID: 33673144 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-MARV VP40/Marburg VP40 polyclonal antibody at 1ug/mL on recombinant MARV VP40/Marburg VP40 (Catalog No. VK735012).
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