

| Catalog No. | HC577014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MCL1 Polyclonal Antibody (HC577014) is a rabbit polyclonal antibody detecting MCL1 in ELISA, IHC, WB. Suitable for Human, Dog, and Cat.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MCL1 (Arg6-Ile328). | ||||||||
| Target | mcl1/EAT, Bcl2-L-3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, BCL2L3, Bcl-2-related protein EAT/mcl1, MCL1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q07820 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) is a ~37 kDa protein. Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. | ||||||||
| Note | For research use only. |
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