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Anti-MCL1 Polyclonal Antibody (HC577014)

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Overview
Catalog No.HC577014
Description
Anti-MCL1 Polyclonal Antibody (HC577014) is a rabbit polyclonal antibody detecting MCL1 in ELISA, IHC, WB. Suitable for Human, Dog, and Cat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human MCL1 (Arg6-Ile328).
Target mcl1/EAT, Bcl2-L-3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, BCL2L3, Bcl-2-related protein EAT/mcl1, MCL1
Purification Purified by antigen affinity column.
Accession Q07820
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) is a ~37 kDa protein. Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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