

| Catalog No. | VK448014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MeV M/Matrix Polyclonal Antibody (VK448014) is a rabbit polyclonal antibody detecting Matrix protein in WB, IHC, ELISA. Suitable for Measles virus (MeV).
Highlights
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| Species reactivity | Measles virus (MeV) | ||||||||
| Applications | WB, IHC, ELISA | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant MeV M/Matrix (Met1-Leu335). | ||||||||
| Target | Matrix protein | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purity | >90% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9W850 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Matrix protein, M | ||||||||
| Background | Matrix protein is a ~37 kDa protein. The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane. Associates with phosphatidylserine (PS) and phosphatidylinositol 4,5-bisphosphate (PIP2) at the plasma membrane. Interaction with PIP2 triggers matrix protein lattice polymerization. Matrix proteins induce host membrane deformation and curvature necessary for virion assembly/budding. 1. Norris, MJ. et al. (2022) Science advances 8, eabn1440. PMID: 35857835 | ||||||||
| Note | For research use only. |
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