Anti-MFN1 Polyclonal Antibody (HA938014)

Name: Anti-MFN1 Polyclonal Antibody
Brand: abinScience
SKU: HA938014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HA938014

Description

Anti-MFN1 Polyclonal Antibody (HA938014) is a rabbit polyclonal antibody detecting MFN1 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant MFN1 (Met1-Gly298).

Target

EC:3.6.5.-, Fzo homolog, MFN1, Mitofusin-1, Transmembrane GTPase MFN1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q8IWA4, Q8R4Z9, Q811U4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Mitofusin-1 (MFN1) is a ~84 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro).

1. Legros, F. et al. (2002) Molecular biology of the cell 13, 4343-54. PMID: 12475957

2. Santel, A. et al. (2003) Journal of cell science 116, 2763-74. PMID: 12759376

3. Qi, Y. et al. (2016) The Journal of cell biology 215, 621-629. PMID: 27920125

4. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303

Note

For research use only

Images

References

Datasheet

Anti-MFN1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-MFN1 Polyclonal Antibody (HA938014)

Overview

Images

References

Datasheet

SDS