

| Catalog No. | JN128014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mgp3 Polyclonal Antibody (JN128014) is a rabbit polyclonal antibody detecting Mgp-operon protein 3; Mgp3; ORF-3 protein; MG192 in ELISA, IHC, WB.
Highlights
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| Species reactivity | Mycoplasma genitalium | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mgp3 (Asn26-Asp408). | ||||||||
| Target | Mgp-operon protein 3; Mgp3; ORF-3 protein; MG192 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P22747 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Adhesin P110 (Mgp3) is a ~114 kDa protein. Part of the major adhesin Nap complex which mediates attachment to host ciliated epithelium. This protein and P140 (mgpB) mutually stabilize each other, and are required for formation of the attachment organelle. Binds sialylated oligosaccharides, which are present on the surface of its human host cells and which probably serve as the main host cell receptors for this bacterium. The Nap complex plays a major role in gliding motility and adhesion to host cells. 1. Burgos, R. et al. (2006) Journal of bacteriology 188, 8627-37. PMID: 17028283 2. Aparicio, D. et al. (2018) Nature communications 9, 4471. PMID: 30367053 3. Marseglia, A. et al. (2024) International journal of biological macromolecules 279, 135277. PMID: 39226978 4. García-Morales, L. et al. (2016) Molecular microbiology 100, 125-38. PMID: 26712501 5. Seybert, A. et al. (2018) Molecular microbiology 108, 319-329. PMID: 29470847 6. Aparicio, D. et al. (2020) Nature communications 11, 2877. PMID: 32513917 | ||||||||
| Note | For research use only |
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