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Anti-MMP1 Polyclonal Antibody (HY437014)

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Overview
Catalog No.HY437014
Description
Anti-MMP1 Polyclonal Antibody (HY437014) is a rabbit polyclonal antibody detecting MMP1 in ELISA, IHC, WB. Suitable for Human, Bovine, Equus caballus, and Pig.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human MMP1 (Phe20-Asn469).
Target MMP1, MMP-1, Matrix metalloproteinase-1, CLG, Interstitial collagenase, Fibroblast collagenase
Purification Purified by antigen affinity column.
Accession P03956
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Interstitial collagenase (MMP1) is a ~54 kDa protein. Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.

1. Desrochers, PE. et al. (1991) The Journal of clinical investigation 87, 2258-65. PMID: 1645757
2. Springman, EB. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 364-8. PMID: 2153297
3. Clark, IM. et al. (1989) The Biochemical journal 263, 201-6. PMID: 2557822
4. Rumbaugh, J. et al. (2006) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1736-8. PMID: 16807369
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-MMP1 Polyclonal Antibody

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