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Anti-Mouse ADGRB1/BAI1 Polyclonal Antibody (MT218014)

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Overview
Catalog No.MT218014
Description
Anti-Mouse ADGRB1/BAI1 Polyclonal Antibody (MT218014) is a rabbit polyclonal antibody detecting Adgrb1. Suitable for Rat, Mouse, and Human.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse ADGRB1/BAI1 (Ser636-Thr940).
Target Adgrb1, Adhesion G protein-coupled receptor B1, Bai1, Brain-specific angiogenesis inhibitor 1, Vasculostatin-120, Vasculostatin-40, Vstat-40, Vstat120
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q3UHD1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Adhesion G protein-coupled receptor B1 (ADGRB1/BAI1) is a ~173 kDa protein. Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion.

1. Park, D. et al. (2007) Nature 450, 430-4. PMID: 17960134
2. Das, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 2136-41. PMID: 21245295
3. Billings, EA. et al. (2016) Science signaling 9, ra14. PMID: 26838550
4. Hochreiter-Hufford, AE. et al. (2013) Nature 497, 263-7. PMID: 23615608
5. Zhu, D. et al. (2015) The Journal of clinical investigation 125, 1497-508. PMID: 25751059
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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