Anti-Mouse APOE Recombinant Antibody (HJ6.3) (MF739013)

Name: Anti-Mouse APOE Recombinant Antibody (HJ6.3)
Brand: abinScience
SKU: MF739013
Price: 110 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	MF739013
Species reactivity	Mouse
Applications	Blocking, IHC
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	HJ6.3
Clonality	Monoclonal
Target	Apo-E, Apolipoprotein E, APOE
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P08226
RRID	Anti-Mouse APOE Antibody (HJ6.3) (abinScience Cat# MF739013, RRID:AB_3725650)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Apolipoprotein E (APOE) is a ~35 kDa protein. APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. 1. Gonzales, JC. et al. (2013) The Journal of clinical investigation 123, 2742-51. PMID: 23676495
Note	For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Mouse APOE Antibody (HJ6.3).
SDS-PAGE

SDS-PAGE for Anti-Mouse APOE Antibody (HJ6.3).
Western blot

Western blot analysis was performed using anti-APOE monoclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse heart lysate