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Anti-Mouse Arl13b Polyclonal Antibody (MS942014)

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Overview
Catalog No.MS942014
Description
Anti-Mouse Arl13b Polyclonal Antibody (MS942014) is a rabbit polyclonal antibody detecting ARL13B. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse Arl13b (Met1-Ser241).
Target ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q640N2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

ADP-ribosylation factor-like protein 13B (Arl13b) is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling.

1. Higginbotham, H. et al. (2013) Nature neuroscience 16, 1000-7. PMID: 23817546
2. Higginbotham, H. et al. (2012) Developmental cell 23, 925-38. PMID: 23153492
Note For research use only
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Formula
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Anti-Mouse Arl13b Polyclonal Antibody

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