

| Catalog No. | MB666013 |
|---|---|
| Description |
Anti-Mouse CD11c Recombinant Antibody (N418) (MB666013) is a rat monoclonal antibody detecting CD11c in in vivo targeting of DC, Functional assays, IHC-Fr, IHC-P, IF, IP. Suitable for Mouse.
Highlights
|
| Species reactivity | Mouse |
| Applications | in vivo targeting of DC, Functional assays, IHC-Fr, IHC-P, IF, IP |
| Host species | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Clone ID | N418 |
| Target | CD11 antigen-like family member C, CD11c, Integrin alpha-X, Itgax, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95 |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q9QXH4 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Integrin alpha-X (CD11c) is a ~129 kDa protein. Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Functions as a receptor of the erythrocyte-specific adhesion molecule ICAM4 and mediates erythrophagocytosis. |
| Note | For research use only. |
| Isotype Control | Rat IgG2a Recombinant Isotype Control Antibody (SPE-7) (RF533107) |

SDS-PAGE for Anti-Mouse CD11c/ITGAX Antibody (N418)




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