Anti-Mouse CD14 Polyclonal Antibody (MY038014)

Name: Anti-Mouse CD14 Polyclonal Antibody
Brand: abinScience
SKU: MY038014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

MY038014

Description

Anti-Mouse CD14 Polyclonal Antibody (MY038014) is a rabbit polyclonal antibody detecting CD14 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD14 (Glu21-Gly322).

Target

Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14

Purification

Purified by antigen affinity column.

Accession

P10810

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Monocyte differentiation antigen CD14 is a ~39 kDa protein. Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Acts as an accessory receptor for M.tuberculosis lipoproteins LprA, LprG and LpqH, in conjunction with coreceptors TLR2 and TLR1.

1. Gangloff, SC. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 3940-5. PMID: 16148141

2. Jiang, Z. et al. (2005) Nature immunology 6, 565-70. PMID: 15895089

3. Haziot, A. et al. (1996) Immunity 4, 407-14. PMID: 8612135

4. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712

Note

For research use only.

Images

References

Datasheet

Anti-Mouse CD14 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD14 Polyclonal Antibody (MY038014)

Overview

Images

References

Datasheet

SDS

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