

| Catalog No. | MW664014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse CD147/BSG (Ala22-Arg325). | ||||||||
| Tested applications | WB | ||||||||
| Target | Basigin (Basic immunoglobulin superfamily) (HT7 antigen) (Membrane glycoprotein gp42) (CD antigen CD147) | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P18572 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. 1. Hori, K. et al. (2000) Investigative ophthalmology & visual science 41, 3128-33. PMID: 10967074 2. Ochrietor, JD. et al. (2001) Experimental eye research 72, 467-77. PMID: 11273674 3. Ochrietor, JD. et al. (2002) Vision research 42, 447-53. PMID: 11853760 4. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-BSG polyclonal antibody at 1ug/mL on various samples.
Lane 1: U87 cell lysate
Lane 2: Mouse spleen lysate
Lane 3: Mouse heart lysate
Lane 4: Mouse liver lysate
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