Anti-Mouse CD275/ICOSLG Polyclonal Antibody (MF564014)

Name: Anti-Mouse CD275/ICOSLG Polyclonal Antibody
Brand: abinScience
SKU: MF564014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

MF564014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD275/ICOSLG (Glu47-Gln258).

Target

ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275)

Purification

Purified by antigen affinity column.

Accession

Q9JHJ8

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

ICOS ligand (CD275/ICOSLG) is a ~35 kDa protein. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.

1. Swallow, MM. et al. (1999) Immunity 11, 423-32. PMID: 10549624

2. Yoshinaga, SK. et al. (1999) Nature 402, 827-32. PMID: 10617205

3. Ling, V. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 1653-7. PMID: 10657606

Note

For research use only.

Images

References

Datasheet

Anti-Mouse CD275/ICOSLG Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD275/ICOSLG Polyclonal Antibody (MF564014)

Overview

Images

References

Datasheet

SDS

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