Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382) (MT188023)

Name: Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382)
Brand: abinScience
SKU: MT188023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MT188023

Species reactivity

Mouse

Applications

ELISA

Host species

Mouse

Isotype

VHH-mFc

Clone ID

SAA2382

Clonality

Monoclonal

Target

Toll-like receptor 2, CD282, Tlr2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9QUN7

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.

1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042

2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091

3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712

4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456

5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CD282/TLR2 Antibody (SAA2382)

References

Datasheet

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382) (MT188023)

Overview

Images

References

Datasheet

SDS

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