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Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3) (MT070207)

Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)
Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)
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Overview
Catalog No.MT070207
Species reactivityHuman, Mouse
ApplicationsELISA, FCM
Host speciesRat
IsotypeIgG1, kappa
Clone IDYW64.3
Clonality Monoclonal
Target NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P97333
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. He, W. et al. (2015) Nature 526, 710-4. PMID: 26503042
Note For research use only.
Images
  • Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD304/NRP1 Antibody (YW64.3)

References
Formula
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