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Anti-Mouse CD309/KDR/VEGFR-2 Recombinant Antibody (DC101) (MW338107)

Anti-Mouse CD309/KDR/VEGFR-2 Recombinant Antibody (DC101)
Anti-Mouse CD309/KDR/VEGFR-2 Recombinant Antibody (DC101)
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Overview
Catalog No.MW338107
Species reactivityMouse
ApplicationsFCM, Neutralization, WB
Host speciesRat
IsotypeIgG1, kappa
Clone IDDC101
Clonality Monoclonal
Target FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P35918
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).

Note For research use only.
Images
  • Anti-Mouse CD309/KDR/VEGFR-2 Recombinant Antibody (DC101)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD309/KDR/VEGFR-2 Antibody (DC101)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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