Anti-Mouse αVβ6 Recombinant Antibody (7.1G10), PE (MY065127)

Name: Anti-Mouse αVβ6 Recombinant Antibody (7.1G10), PE
Brand: abinScience
SKU: MY065127
Price: 256 USD
Availability: InStock

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Overview

Catalog No.	MY065127
Description	Anti-Mouse αVβ6 Recombinant Antibody (7.1G10), PE (MY065127) is a mouse monoclonal antibody detecting αVβ6 in ELISA, FCM. Suitable for Human, Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Multi-Species — Cross-reactive for translational research. ●PE Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	Human, Mouse
Applications	ELISA, FCM
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	7.1G10
Conjugation	PE
Target	MSK8, VNRA, Vitronectin receptor, Integrin alpha-V, Vitronectin receptor subunit alpha, CD51, ITGAV, VTNR, ITGB6, Integrin beta-6
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Associated products	Mouse IgG2a kappa Recombinant kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Accession	P43406(Itgav) & Q9Z0T9(Itgb6)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	αVβ6 is a protein, also known as Bispecific, STX-100, STX100, STX100. STX-100 (1 h pretreatment) exhibits minimal inhibitory effects on TGF-β1-induced morphological and nuclear changes in A549 cells [3]. STX-100 (1 h pretreatment) does not substantially alter actin cytoskeletal organization in A549 cells and does not prevent TGF-β1-associated changes in actin distribution [3]. STX-100 (1 h pretreatment) has limited inhibitory effects on TGF-β1-induced morphological and nuclear changes in MCF10A cells [3]. STX-100 (1 h pretreatment) does not reverse TGF-β1-induced changes in cell organization, cell-cell adhesion, nuclear morphology, or extracellular matrix structure in MCF10A cells [3]. STX-100 (1 h pretreatment) does not substantially alter TGF-β1-driven changes in fibronectin fibril organization in MCF10A cells [3]. STX-100 (3 mg/kg; s.c.; weekly; 8 weeks) promotes acute renal allograft rejection in rhesus macaques [2].
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse αVβ6 Recombinant Antibody (7.1G10), PE.pdf

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Anti-Mouse αVβ6 Recombinant Antibody (7.1G10), PE (MY065127)

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