

| Catalog No. | MY570014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse CD79α/CD79A Polyclonal Antibody (MY570014) is a rabbit polyclonal antibody detecting CD79a in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse CD79α/CD79A (Ser37-Asn121). | ||||||||
| Target | Surface IgM-associated protein, CD79a, Membrane-bound immunoglobulin-associated protein, MB1, MB-1 membrane glycoprotein, IGA, CD79A, Ig-alpha, B-cell antigen receptor complex-associated protein alpha chain | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P11911 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | B-cell antigen receptor complex-associated protein alpha chain (CD79α/CD79A) is a ~24 kDa protein. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. | ||||||||
| Note | For research use only. |
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