Anti-Mouse CD84/SLAMF5 Polyclonal Antibody (MV297014)

Name: Anti-Mouse CD84/SLAMF5 Polyclonal Antibody
Brand: abinScience
SKU: MV297014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

MV297014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD84 (Met27-Gln206).

Target

SLAM family member 5 (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)

Purification

Purified by antigen affinity column.

Accession

Q18PI6

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

SLAM family member 5 (CD84) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process.

1. Wang, N. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 5683-7. PMID: 20962259

2. Cannons, JL. et al. (2010) Immunity 32, 253-65. PMID: 20153220

3. Wong, EB. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4130-43. PMID: 25801429

4. Sintes, J. et al. (2010) Journal of leukocyte biology 88, 687-97. PMID: 20628063

Note

For research use only.

Images

References

Datasheet

Anti-Mouse CD84/SLAMF5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD84/SLAMF5 Polyclonal Antibody (MV297014)

Overview

Images

References

Datasheet

SDS

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