Anti-Mouse COMP Recombinant Antibody (15A11) (MW810013)

Name: Anti-Mouse COMP Recombinant Antibody (15A11)
Brand: abinScience
SKU: MW810013
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MW810013

Species reactivity

Mouse, Rat

Applications

ELISA, IHC

Host species

Mouse

Isotype

IgG1

Clone ID

15A11

Clonality

Monoclonal

Target

TSP5, Thrombospondin-5, COMP, Cartilage oligomeric matrix protein

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9R0G6

RRID

Anti-Mouse COMP Antibody (15A11) (abinScience Cat# MW810013, RRID:AB_3725643)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Cartilage oligomeric matrix protein (COMP) is a ~82 kDa protein. Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).

1. Li, C. et al. (2020) Nature communications 11, 3642. PMID: 32686688

Note

For research use only.

Images

Bioactivity

SEC-HPLC detection for Anti-Mouse COMP Antibody (15A11).
SDS-PAGE

SDS-PAGE for Anti-Mouse COMP Antibody (15A11).

References

Datasheet

Anti-Mouse COMP Recombinant Antibody (15A11).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse COMP Recombinant Antibody (15A11) (MW810013)

Overview

Images

References

Datasheet

SDS

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