

| Catalog No. | MV571014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse DLL4 Polyclonal Antibody (MV571014) is a rabbit polyclonal antibody detecting DLL4 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse DLL4 (Gly27-Ser177). | ||||||||
| Target | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9JI71 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. 1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954 2. Luo, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E553-62. PMID: 22323600 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-DLL4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat lung lysate
Lane 2: Rat kidney lysate
Lane 3: Rat pancears lysate




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