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Anti-Mouse EDA1 Recombinant Antibody (SAA2721) (MP033023)

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Overview
Catalog No.MP033023
Species reactivityMouse
ApplicationsELISA, FCM, WB
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA2721
Clonality Monoclonal
Target EDA protein homolog, Ectodysplasin-A, Ectodysplasin-A, membrane form, Ectodysplasin-A, secreted form, Ed1, Eda, Ta, Tabby protein
Endotoxin level <10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession O54693
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Ectodysplasin-A (EDA1) is a ~41 kDa protein. Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R. Isoform TAA binds only to the receptor EDAR, while isoform TA-A2 binds exclusively to the receptor EDA2R. May also play a role in cell adhesion.

1. Mikkola, ML. et al. (1999) Mechanisms of development 88, 133-46. PMID: 10534613
Note For research use only
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