Anti-Mouse EPOR Polyclonal Antibody (MB152014)

Name: Anti-Mouse EPOR Polyclonal Antibody
Brand: abinScience
SKU: MB152014
Price: 168 USD
Availability: InStock

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Price(USD): $

Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MB152014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse EPOR (Asp32-Thr243).

Target

Erythropoietin receptor (EPO-R)

Purification

Purified by antigen affinity column.

Accession

P14753

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

1. D'Andrea, AD. et al. (1989) Cell 57, 277-85. PMID: 2539263

2. Sawyer, ST. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 6849-53. PMID: 8341708

3. Miura, O. et al. (1993) Molecular and cellular biology 13, 1788-95. PMID: 8382775

4. Hilton, DJ. et al. (1996) The Journal of biological chemistry 271, 4699-708. PMID: 8617735

5. Chin, H. et al. (1998) Blood 91, 3734-45. PMID: 9573010

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Mouse EPOR polyclonal antibody at 1ug/mL on recombinant Mouse EPOR (Catalog No. MB152012).

References

Datasheet