

| Catalog No. | MA012014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse ERRFI1 Polyclonal Antibody (MA012014) is a rabbit polyclonal antibody detecting Errfi1 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse ERRFI1 (Ser329-Arg399). | ||||||||
| Target | ERBB receptor feedback inhibitor 1, Mitogen-inducible gene 6 protein homolog, MIG-6, Errfi1, Mig6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q99JZ7 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | ERBB receptor feedback inhibitor 1 (ERRFI1) is a ~50 kDa protein. Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. | ||||||||
| Note | For research use only. |
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