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Anti-Mouse F2RL1 Polyclonal Antibody (MX041014)

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Anti-Mouse F2RL1 Polyclonal Antibody
Anti-Mouse F2RL1 Polyclonal Antibody
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Overview
Catalog No.MX041014
Description
Anti-Mouse F2RL1 Polyclonal Antibody (MX041014) is a rabbit polyclonal antibody detecting Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse F2RL1 (Ser39-Gly73&Met214-Leu237&Ser350-Tyr399).
Target Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P55086
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Proteinase-activated receptor 2 (F2RL1) is a ~44 kDa protein. Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2r/Par1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation.

1. Borensztajn, K. et al. (2008) The American journal of pathology 172, 309-20. PMID: 18202198
Note For research use only
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  • Anti-Mouse F2RL1 Polyclonal Antibody

    Western blot

    Lane 1: Mouse kidney lysate

References
Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Mouse F2RL1 Polyclonal Antibody

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