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Anti-Mouse FABP5 Polyclonal Antibody (MX954014)

Anti-Mouse FABP5 Polyclonal Antibody
Anti-Mouse FABP5 Polyclonal Antibody
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Overview
Catalog No.MX954014
Description
Anti-Mouse FABP5 Polyclonal Antibody (MX954014) is a rabbit polyclonal antibody detecting FABP5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse FABP5 (Met1-Gln135).
Target Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP
Purification Purified by antigen affinity column.
Accession Q05816
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Fatty acid-binding protein 5 (FABP5) is a ~15 kDa protein. Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation.

1. Maeda, K. et al. (2003) Diabetes 52, 300-7. PMID: 12540600
2. Kane, CD. et al. (1996) Biochemistry 35, 2894-900. PMID: 8608126
3. Schug, TT. et al. (2007) Cell 129, 723-33. PMID: 17512406
4. Haj-Dahmane, S. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 3482-3487. PMID: 29531087
5. Bogdan, D. et al. (2018) The Journal of biological chemistry 293, 5295-5306. PMID: 29440395
Note For research use only.
Images
  • Anti-Mouse FABP5 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-FABP5 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate
    Lane 2: Mouse skin lysate
    Lane 3: Rat brain lysate
    Lane 4: Rat liver lysate

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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