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Anti-Mouse FGA Polyclonal Antibody (MF809014)

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Overview
Catalog No.MF809014
Description
Anti-Mouse FGA Polyclonal Antibody (MF809014) is a rabbit polyclonal antibody detecting Fga. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse FGA (Thr552-Gln789).
Target Fga, Fibrinogen alpha chain, Fibrinopeptide A
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession E9PV24
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Fibrinogen alpha chain (FGA) is a ~87 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.

1. Suh, TT. et al. (1995) Genes & development 9, 2020-33. PMID: 7649481
2. Drew, AF. et al. (2001) Blood 97, 3691-8. PMID: 11389004
3. Ni, H. et al. (2000) The Journal of clinical investigation 106, 385-92. PMID: 10930441
4. Yang, H. et al. (2009) Blood 114, 425-36. PMID: 19332769
5. Johnson, LL. et al. (2003) The Journal of experimental medicine 197, 801-6. PMID: 12629066
6. Luo, D. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4149-61. PMID: 23487423
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Mouse FGA Polyclonal Antibody

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