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Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013)

Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)
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Overview
Catalog No.MV462013
Description
Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22) (MV462013) is a mouse monoclonal antibody detecting FGF13/FHF2 in FCM, IF, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsFCM, IF, IHC, WB
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone IDN235/22
Target FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P70377
RRID Anti-Mouse FGF13 Antibody (N235/22) (abinScience Cat# MV462013, RRID:AB_3725654)
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling.

1. Wu, QF. et al. (2012) Cell 149, 1549-64. PMID: 22726441
2. Wang, C. et al. (2011) Circulation research 109, 775-82. PMID: 21817159
3. Schoorlemmer, J. et al. (2001) Current biology : CB 11, 793-7. PMID: 11378392
4. Schoorlemmer, J. et al. (2002) The Journal of biological chemistry 277, 49111-9. PMID: 12244047
5. Favuzzi, E. et al. (2019) Science (New York, N.Y.) 363, 413-417. PMID: 30679375
Note For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Images
  • Anti-Mouse FGF13/FHF2 Recombinant Antibody (N235/22)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse FGF13 Antibody (N235/22).

References
Formula
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