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Anti-Mouse GCGR Recombinant Antibody (mAb1), PE (MW547127)

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Overview
Catalog No.MW547127
Species reactivityHuman, Mouse
ApplicationsELISA, FCM
Host speciesRat
IsotypeIgG1, kappa
Clone IDmAb1
ConjugationPE
Clonality Monoclonal
Target GCGR, Glucagon receptor, GL-R
Endotoxin level Please contact with the lab for this information.
Associated products Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), PE
Accession Q61606
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Glucagon receptor (GCGR) is a ~54 kDa protein. G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase.

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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