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Anti-Mouse GPVI Polyclonal Antibody (MV664014)

Anti-Mouse GPVI Polyclonal Antibody
Anti-Mouse GPVI Polyclonal Antibody
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Overview
Catalog No.MV664014
Description
Anti-Mouse GP6 Polyclonal Antibody (MV664014) is a rabbit polyclonal antibody detecting GP6. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Mouse GP6 (Ser101-Leu206).
Target GP6, GPVI, Glycoprotein 6, Platelet glycoprotein VI
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Accession P0C191
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Platelet glycoprotein VI (GP6) is a ~34 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.

1. Lockyer, S. et al. (2006) Thrombosis research 118, 371-80. PMID: 16139873
2. Pokidysheva, E. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 161-6. PMID: 24368846
Note For research use only
Images
  • Anti-Mouse GPVI Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-GP6 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: SH-SY5Y cell lysate

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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