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Anti-Mouse GP6 Polyclonal Antibody (MV664014)

Anti-Mouse GP6 Polyclonal Antibody
Anti-Mouse GP6 Polyclonal Antibody
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Overview
Catalog No.MV664014
Description
Anti-Mouse GP6 Polyclonal Antibody (MV664014) is a rabbit polyclonal antibody detecting GP6. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse GP6 (Ser101-Leu206).
Target GP6, GPVI, Glycoprotein 6, Platelet glycoprotein VI
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P0C191
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Platelet glycoprotein VI (GP6) is a ~34 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.

1. Lockyer, S. et al. (2006) Thrombosis research 118, 371-80. PMID: 16139873
2. Pokidysheva, E. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 161-6. PMID: 24368846
Note For research use only
Images
  • Anti-Mouse GP6 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-GP6 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: SH-SY5Y cell lysate

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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