

| Catalog No. | MX911014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse HAMP/Hepcidin Polyclonal Antibody (MX911014) is a rabbit polyclonal antibody detecting Hepcidin in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse HAMP/Hepcidin (Thr24-Thr83). | ||||||||
| Target | Hepcidin, Hamp, Hamp1, Hepc, Hepc1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9EQ21 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Hepcidin (HAMP) is a ~9 kDa protein. Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. | ||||||||
| Note | For research use only. |
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