Anti-Mouse IL1A/IL1F1 Polyclonal Antibody (MF802014)

Name: Anti-Mouse IL1A/IL1F1 Polyclonal Antibody
Brand: abinScience
SKU: MF802014
Price: 168 USD
Availability: InStock

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Price(USD): $

Spec:

50ug
100ug

Number:

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MF802014

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL1A/IL1F1 (Met1-Ser161).

Target

Interleukin-1, Il1a

Purification

Purified by antigen affinity column.

Accession

P01582

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-1 alpha (IL1A/IL1F1) is a ~31 kDa protein. Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage.

1. Honore, P. et al. (2006) Behavioural brain research 167, 355-64. PMID: 16256210

2. Stylianou, E. et al. (1992) The Journal of biological chemistry 267, 15836-41. PMID: 1386364

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Mouse IL1A/IL1F1 polyclonal antibody at 1ug/mL on recombinant Mouse IL1A/IL1F1 (Catalog No. MF802012).

References

Datasheet

Anti-Mouse IL1A/IL1F1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse IL1A/IL1F1 Polyclonal Antibody (MF802014)

Overview

Images

References

Datasheet

SDS

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