Anti-Mouse IL34 Recombinant Antibody (FAb1.1) (MV955023)

Name: Anti-Mouse IL34 Recombinant Antibody (FAb1.1)
Brand: abinScience
SKU: MV955023
Price: 110 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

MV955023

Species reactivity

Human, Mouse

Applications

ELISA, FCM

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

FAb1.1

Clonality

Monoclonal

Target

IL34, Interleukin-34, C16orf77, IL-34

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8R1R4

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Interleukin-34 (IL34) is a ~26 kDa protein. Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

Note

For research use only.

Images

Flow Cytometry

Flow-cytometry using anti-mouse IL34 antibody.IL34 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-mouse IL34 antibody monoclonal antibody (Catalog # MV955023 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Anti-Mouse IL34 Antibody (FAb1.1).