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Anti-Mouse ITGB8 Polyclonal Antibody (MB904014)

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Overview
Catalog No.MB904014
Description
Anti-Mouse ITGB8 Polyclonal Antibody (MB904014) is a rabbit polyclonal antibody detecting Itgb8 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse ITGB8 (Val106-Ser466).
Target Integrin beta-8, Itgb8
Purification Purified by antigen affinity column.
Accession Q0VBD0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Integrin beta-8 (ITGB8) is a ~84 kDa protein. Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis.

1. Edwards, JP. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2843-9. PMID: 25127859
2. Zhu, J. et al. (2002) Development (Cambridge, England) 129, 2891-903. PMID: 12050137
3. Proctor, JM. et al. (2005) The Journal of neuroscience : the official journal of the Society for Neuroscience 25, 9940-8. PMID: 16251442
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Mouse ITGB8 Polyclonal Antibody

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