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Anti-Mouse MPO Polyclonal Antibody (MY413014)

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Overview
Catalog No.MY413014
Description
Anti-Mouse MPO Polyclonal Antibody (MY413014) is a rabbit polyclonal antibody detecting MPO. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse MPO (Ser289-Thr718).
Target EC:1.11.2.2, MPO, Mpo, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P11247
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Myeloperoxidase (MPO) is a ~81 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low density lipoprotein particles and limits vascular damage.

1. Gaut, JP. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 11961-6. PMID: 11593004
Note For research use only
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Formula
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Anti-Mouse MPO Polyclonal Antibody

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