

| Catalog No. | MF934014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse PLAT/tPA Polyclonal Antibody (MF934014) is a rabbit polyclonal antibody detecting Plat in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse PLAT/tPA (Asp316-Gln559). | ||||||||
| Target | Tissue-type plasminogen activator, t-PA, t-plasminogen activator, tPA, 3.4.21.68, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, Plat | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P11214 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Tissue-type plasminogen activator (PLAT/tPA) is a ~63 kDa protein. Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy. | ||||||||
| Note | For research use only. |
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