

| Catalog No. | MB687013 | ||||||
|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||
| Applications | ELISA, IP, WB | ||||||
| Host species | Rat | ||||||
| Isotype | IgG1, kappa | ||||||
| Clone ID | SAA0275 | ||||||
| Clonality | Monoclonal | ||||||
| Target | Phosphoinositide phospholipase C-gamma-1, PLC1, PLC-II, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC-148, PLCG1, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1 | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purity | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Accession | Q62077 | ||||||
| RRID | Anti-Mouse PLCG1 Antibody (SAA0275) (abinScience Cat# MB687013, RRID:AB_3725646) |
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| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Background | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) is a ~149 kDa protein. Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis. | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Mouse PLCG1 Antibody (SAA0275)
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