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Anti-Mouse PLG Polyclonal Antibody (MF499014)

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Overview
Catalog No.MF499014
Description
Anti-Mouse PLG Polyclonal Antibody (MF499014) is a rabbit polyclonal antibody detecting PLG. Suitable for Mouse and Rat.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse PLG (Cys568-Asn812).
Target Activation peptide, Angiostatin, EC:3.4.21.7, PLG, Plasmin heavy chain A, Plasmin heavy chain A, short form, Plasmin light chain B, Plasminogen
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P20918
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Plasminogen (PLG) is a ~90 kDa protein. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1, C4 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor.

Note For research use only
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Formula
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Formula
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