

| Catalog No. | MA272014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse PLXNB3 Polyclonal Antibody (MA272014) is a rabbit polyclonal antibody detecting PLXNB3 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse PLXNB3 (Cys464-Asp609). | ||||||||
| Target | PLXNB3, Plexin-B3, PLXN6, KIAA1206 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9QY40 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Plexin-B3 (PLXNB3) is a ~208 kDa protein. Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. Seem to be non-essential for normal development and function of the central nervous system. | ||||||||
| Note | For research use only. |
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